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Prognostic significance of CD8+ T cell Spatial Biomarkers in ER+ and ER− breast cancer: A retrospective cohort study

October 15, 2025

Prognostic significance of CD8+ T cell Spatial Biomarkers in ER+ and ER− breast cancer: A retrospective cohort study

Andrew E. Walker and colleagues examine proximity and consistency as spatial metrics of CD8+ T cells within the breast cancer immune microenvironment. The team evaluates the metrics' associations with breast cancer prognosis in both ER+ and ER- breast cancers.

Image credit: Pexels, Edward Jenner

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PLOS Medicine | ISSN: 1549-1676 (online)